472 Wheelers Farms Road, Suite 306, Milford, CT 06461 | 8:00 AM to 5:30PM

IV Ketamine & Spravato™

Depression Psychiatrist in Milford Connecticut

IV Ketamine & Spravato™

Spravato and IV Ketamine depression treatment are used to care for patients with treatment resistant depression. IV Ketamine and Spravato are administered within our offices where you will be monitored by a psychiatrist and other medical professionals over the course for 60 to 120 minutes.

Schedule a Consult

An intravenous mixture of two mirror-image molecules: “R” and “S” ketamine used for treatment-resistant depression.


The first nasal spray medication, taken along with an oral antidepressant, for adults with
treatment-resistant depression.

Ketamine Depression Treatment

It has been discovered that ketamine can be highly effective in treating depression, PTSD, Fibromyalgia, and other conditions.
Ketamine depression treatment is different from any other antidepressant medication and has up to an 80% effectivity rate. Ketamine works on a neurotransmitter called Glutamate which leads to the production a growth factor helping the brain repair damaged neurons. These neurons are affected by stress and untreated mental illness. Ketamine, can often improve mood quickly and also cause the regeneration of nerve cells over time. 

IV Ketamine FAQs

Is Ketamine depression treatment Safe?

Ketamine is a FDA approved and primarily as an induction agent for general anesthesia in surgery for children, adults, and animals. Ketamine has a remarkable safety track record.

What is the success rate of Ketamine treating depression?

Ketamine is 60-80 % effective for depression. Although the effects of Ketamine usually last for several weeks, some people can remain in remission for months.

Do I need a referral from my primary care physician?

No, you do not need a referral.

What is the minimum age for treatment?

Every center is different. If you yourself are younger or the parent of a younger patient that is considering IV Ketamine as treatment for depression feel free to call our office 203-701-9737. We will be happy to discuss available treatments for all age groups. 

What disorders can ketamine infusions treat?

Promising data has demonstrated positive effects in treating severe, chronic, treatment resistant depression. Depression MD uses Ketamine for major depression, bipolar depression, postpartum depression, OCD and Anxiety.

Are there any specific medical conditions that would prevent me from receiving treatment?

If you have psychosis, high blood pressure, cardiac, and/or pulmonary issues it may be necessary for your primary care physician to provide a medical clearance before beginning ketamine.

Can I eat and/or drink prior to my Ketamine infusion?

Avoid solid foods and/or milk for 6 hours prior to your ketamine infusion. You may drink clear liquids (i.e. water, fruit juices without pulp, carbonated beverages, clear tea, and black coffee) up until 2 hours before your infusion. Alcohol or the use of any narcotic drugs must be excluded. These substances are extremely dangerous in combination with ketamine.

Will I be asleep during the procedure?

No. The dose of ketamine you will receive does not put you to sleep.

What is the infusion process like?

Ketamine is administered intravenously over 45 minutes. As the infusion progresses, you may encounter a feeling of “lightness” or “floating,” which for some feels as a “weight being lifted off their shoulders”. You will be monitored throughout the infusion and we are prepared to treat
any unpleasant side effects during the procedure. Within 15 minutes of completing the infusion, you will to start to regain your senses and your
thinking will return to normal.

How do I know if the infusion worked? How should I expect to feel afterwards?

After the infusion, you may notice positive effects as soon as 30 minutes post
infusion but typically improvements begin several hours post-treatment.

How long will the effects last?

The effects of a single infusion typically last up to two weeks. After a series of six infusions, some people could remain symptom free for several months. Booster infusions can be given monthly or quarterly as needed.

Should I be concerned about any risks of addiction with ketamine therapy?

No, although it has been abused recreationally at much higher doses as a club drug, ketamine is not addictive. Ketamine is proven safe in humans. It has been used for years as a surgical anesthetic in children and in trauma management. In addition, Ketamine will be administered under medical supervision.

logo icon of brain

Depression is treatable, schedule a consultation now!

It’s important for you to be comfortable with us before your first visit. So schedule a quick phone call with any concerns or to discuss the care you need 203-701-9737.

See All ServicesSchedule A Consult

Patient Testimonial

Dr. Harding is a genuinely caring person!!! She is by far the best that Doctor I have seen on SO many levels! This wonderful woman has a TRUE love and passion for what she does and believes in. Dr. Harding has gone out of her way, above and beyond to show me how much she cares! She is a real down to earth person, easy to talk to and LISTENS. I was afraid to see a new resident when she started because of all my past experiences, but she has been the biggest blessing to walk into my life when I needed it the most! I will forever be grateful for her and the beautiful soul that she has I would and WILL always recommend Dr. Harding to ANYONE